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Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA
1 Introduction Venous thromboembolism (VTE), encompassing deep vein thrombosis and pulmonary embolism, commonly emerges as an early complication in various cancers.[1, 2] It affects approximate 15% to 20% of cancer patients, ranking as the second-leading cause of death in this population while significantly impairing their quality of life.[3, 4] The current management approaches for VTE in cancer patients face challenges due to the intricate interactions between anticoagulant therapy and...
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