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Vaccine‐Induced and Hybrid Immunity Against SARS‐CoV‐2 Variants of Concern in Two Cohorts in Queensland, Australia (2021-2022)
Conflicts of Interest The authors declare no conflicts of interest. References 1, , , et al., “Serology Characteristics of SARS-CoV-2 Infection After Exposure and Post-Symptom Onset,” European Respiratory Journal 56 (2020): 2000763, https://doi.org/10.1183/13993003.00763-2020. 2, , and , “The First 12 Months of COVID-19: A Timeline of Immunological Insights,” Nature Reviews Immunology 21 (2021): 245–256, https://doi.org/10.1038/s41577-021-00522-1.
Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022).
Abstract The spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main target for vaccine development, as antibodies generated against the spike protein are the most immunodominant and neutralizing against the virus. However, variants of concern (VOC), often containing multiple mutations within neutralizing epitopes, confer immune evasion of the response generated by current SARS-CoV-2 vaccines.
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