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Yingke Wu on Muck Rack

Yingke Wu

As seen in: Nature, Wiley Online Library, Science Magazine, Royal Society of Chemistry
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Articles

Finding the perfect promoter for Cas9 in homing gene drives using single cell transcriptome data

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By Yingke Wu, Weizhe Chen, Xihua Jia, Nan Liang, Jackson Champer, Yunchen Xia, Ziyin Yao
| Nature Verified
Abstract Gene drive can modify or suppress vector populations by spreading drive alleles. In CRISPR homing drives, regulating Cas9 expression has been effective for improving drive performance, but selecting suitable promoters is often a major challenge. Here, we evaluate 35 Cas9 constructs with distinct promoters in Drosophila melanogaster and identify associations between drive performance and single-cell RNA expression patterns of the promoter-associated genes.
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Bioresponsive microneedle stent provides anastomosis and postoperative adjuvant therapy in preclinical resectable intestinal diseases

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By xiaofan LI, Ruyi Zhou, Keenan A. Walker, Dong Cen, MingYu Chen, Junjie Nan, Jiahuan You, Qiang Zheng, Yingke Wu, Hao Yu, Yong Sun, Yinxian Yang, Wei Zhou, Jie Lin, Huimin An, Qingxuan Ye, Yuewei Chen, Zehao Zeng, Xuxu Yang, Yong He, Peng Teng, Jinqiang Wang, Jicheng Yu, Yuqi Zhang, Zhen Gu
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Resection of diseased bowel requires rejoining of the remaining intestinal segments and postoperative therapy to support a regenerative environment. Here, Zhou et al.
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Bottom-Up Synthesis of Molecular Nanodiamond from Nanographene

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By Jiaxu Liang, Christopher P. Ender, Nancy C. Forero-Martinez, Ilyes Batatia, Jingyi Liu, Xin Yang, Lev Kazak, Rémi Blinder, Leonardo Cancellara, Nadezda V. Tarakina, Yizhi Liu, Sarah Köster, Shrikant Bhat, Andreas Tangemann, Rüdiger Berger, Robert Farla, Alexander Kubanek, Katrin Amann-Winkel, Manfred Wagner, Fedor Jelezko, Klaus Müllen, Gabor Csanyi, Robinson Cortes-Huerto, Yingke Wu, Tanja Weil, Raul Gonzalez Brouwer, Tobias Eklund, Mangalika Sinha, Fabian Rohmann, Kilian Lee Gallo
| Nature Verified
Abstract Nanodiamonds hosting colour centres are promising building blocks for quantum technologies, enabling advances in quantum computation1,2, nanoscale NMR spectroscopy3–6, single-spin magnetometry7,8, wide-field quantum imaging9 and single-photon sources10,11.
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