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Yingke Xu on Muck Rack

Yingke Xu

As seen in: Nature, Wiley Online Library, PLOS, PLOS ONE, Royal Society of Chemistry
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Articles

DOCTER: a genetically encoded switchable protein module for ERα-mediated transcriptional regulation

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By Jinmin Wang, Jingfang Liu, Dandan Peng, Yuhao Ji, Ke Huang, Junfen Fu, Yingke Xu
| Nature Verified
Abstract The inhibition of estrogen receptor (ER)-mediated genomic signaling in ER-positive cancer cells has long been a primary focus of therapeutic strategies. Here, we introduce a switchable competitive inhibition system for ERα-mediated transcriptional regulation, termed DOCTER (Drug-induced On-Off Competitor for Transcription mediated by ERα). DOCTER integrates the Tet-On induced Cre-loxP recombination system to enable precise, reversible on/off switching.
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Application of Super‐Resolution Microscopy in Virology Research: Principles, Technological Advances, and Analysis of the Viral Life Cycle

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By Mengyi Liu, Luhao Zhang, Sha Huang, Yingke Xu
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References 1, “Virus Morphology: Insights From Super-Resolution Fluorescence Microscopy,” Biochimica et Biophysica Acta, Molecular Basis of Disease 1868, no. 4 (2022): 166347, https://doi.org/10.1016/j.bbadis.2022.166347.
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Using machine learning and single nucleotide polymorphisms for improving rheumatoid arthritis risk Prediction in postmenopausal women

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By Yingke Xu, Qing Wu
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Citation: Xu Y, Wu Q (2025) Using machine learning and single nucleotide polymorphisms for improving rheumatoid arthritis risk Prediction in postmenopausal women. PLOS Digit Health 4(4): e0000790.
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