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Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition
Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition Yinglan Guo https://orcid.org/0000-0002-9620-3026, Xin Du https://orcid.org/0000-0002-6907-3609, [...] , Janes Krusche https://orcid.org/0009-0004-1900-8480, Christian Beck https://orcid.org/0009-0006-0062-9628, [...] , Sara Ali, Axel Walter https://orcid.org/0000-0001-9462-9712, Volker Winstel https://orcid.org/0000-0002-3248-2572, Christoph Mayer...
Reply to: Do not discard Staphylococcus aureus WTA as a vaccine antigen
Fig. 1: Structure of S. aureus WTA and its variation by different GlcNAc transferases. References 1. Gerlach, D. et al. Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity. Nature 563, 705–709 (2018). 2. van Dalen, R. et al. Do not discard Staphylococcus aureus WTA as a vaccine antigen. Nature https://doi.org/10.1038/s41586-019-1416-8 (2019). 3. Driguez, P. A. et al. Immunogenic compositions against S. aureus. WO patent WO/2017/064190 (2017). 4. Hütter, J. & Lepenies, B.
Methicillin-resistant <i>Staphylococcus aureus</i> alters cell wall glycosylation to evade immunity
1. Tong, S. Y., Davis, J. S., Eichenberger, E., Holland, T. L. & Fowler, V. G. Jr. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin. Microbiol. Rev. 28, 603–661 (2015). 2. Lee, A. S. et al. Methicillin-resistant Staphylococcus aureus. Nat. Rev. Dis. Primers 4, 18033 (2018). 3. Stentzel, S. et al. Specific serum IgG at diagnosis of Staphylococcus aureus bloodstream invasion is correlated with disease progression. J. Proteomics 128, 1–7 (2015). 4. Missiakas, D.
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