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Comment on Xiaolan Zhang et al
Corresponding Author Qi Chen Department of Pediatrics, Tiantai People's Hospital of Zhejiang Province (Tiantai Branch of Zhejiang Provincial People's Hospital), Hangzhou Medical College, Taizhou, Zhejiang, China Correspondence Qi Chen, Department of Pediatrics, Tiantai People's Hospital of Zhejiang Province (Tiantai Branch of Zhejiang Provincial People's Hospital), Hangzhou Medical College, Taizhou, Zhejiang, China.
Biology of endophilin and it’s role in disease
Introduction The Endophilin family is a group of protein containing SH3 (Src homology 3) structural domain and BAR (Bin-amphiphysin-Rvs) structural domain. This family was first discovered in 1996 (1). It consists of two subfamilies, including Endophilin A and Endophilin B. Endophilin A consists of three isoforms: Endophilin A1, Endophilin A2 and Endophilin A3. Endophilin B consists of two isoforms: Endophilin B1 and Endophilin B2.
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