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Yingli Si on Muck Rack

Yingli Si

As seen in: Frontiers
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Joint effects of leukocyte-albumin ratio and hypertension are associated with multidimensional cognitive decline and Alzheimer’s disease risk in older adults: evidence from NHANES and a clinical AD validation cohort

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By Pan Gao, Nannan Tian, Diandian Diana Chen, Heyang Liu, Peichang Wang, Jingrong Cao, Yiming Chu, Mingjun Geng, Yingli Si
| Frontiers
Abstract Background: Alzheimer’s disease (AD) pathogenesis involves complex interactions between neuroinflammation and vascular dysfunction. While leukocyte-albumin ratio (LAR) and hypertension are independently linked to cognitive decline, their joint associations with multidimensional cognitive impairment and AD risk remain understudied. Methods: We analyzed two cohorts: 1,300 adults (≥ 60 years) from NHANES 2011–2014, and a clinical cohort (50 AD patients + 125 age-/gender-matched controls).
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