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Frontiers | Dynamic trajectories of the triglyceride-glucose index link to all-cause hospital mortality in patients with hypertension and kidney failure: a multicenter study
1 Introduction Chronic kidney disease (CKD) is a global health challenge affecting over 850 million individuals worldwide (1, 2), with 1.2 million deaths attributed to the condition in 2017, and projections indicate this number will rise to 2.2 million by 2040 under best-case scenarios and potentially reach 4.0 million annually in worst-case scenarios (3). Hypertension, a key risk factor for cardiovascular disease and kidney failure (KF), coexists in about 50% of CKD patients (4, 5).
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