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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
C/EBP alpha agonist ICCB280 overcomes doxorubicin resistance in osteosarcoma through mitochondrial dynamics-dependent GREM1-MAPK activation
Abstract The resistance of doxorubicin (DOX), the first-line chemotherapeutic drug for osteosarcoma (OS), stands as a pivotal obstacle in the effective treatment of OS. Alterations in mitochondrial dynamics and thereby affecting reactive oxygen species (ROS) accumulation play critical roles in DOX-induced cell death. However, the novel targets and pharmacological agents combating DOX resistance in OS via mitochondrial homeostasis and DOX-induced cell death manipulation is poorly understood.
FusionDiff: a dual-path diffusion-based framework for few-shot authenticity analysis of ceramic microstructures
Abstract The authenticity of ceramic components is closely tied to their microscopic structures, making automatic and accurate identification essential for quality control. However, this task is often constrained by the scarcity of labeled samples. This study investigates the potential of large-scale pretrained diffusion models as feature extractors, leveraging the rich visual priors embedded in their generative processes to provide a robust semantic foundation for small-sample learning.
Odin: Oriented Dual-module Integration for Text-rich Network Representation Learning
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