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Yingluo Xiong on Muck Rack

Yingluo Xiong

As seen in: Color Research & Application, The Journal of Immunology
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Articles

BLT1 signaling in epithelial cells mediates allergic sensitization via promotion of IL‐33 production

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By Yingluo Xiong, Xinyi Cui, Wenjing Li, Jiaoyan Lv
| Color Research & Application Verified
Background Epithelial cells (ECs) play a crucial role in allergic sensitization to inhaled protease allergens by instructing type 2 innate lymphoid cells (ILC2) and dendritic cells (DCs) via release of pro‐type 2 cytokines, particularly interleukin‐33 (IL‐33). Leukotriene B4 (LTB4) is a well‐known leukocyte chemoattractant via engagement of its receptor 1 (BLT1). However, the role of LTB4‐BLT1 axis in allergic sensitization via activation of ECs is still unknown.
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IL-37 inhibits IL-4/IL-13-induced CCL11 production and lung eosinophilia in murine allergic asthma

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By Jiaoyan Lv, Yingluo Xiong, Wenjing Li, Xunjia Cheng, Rui He, Xinyi Cui, Qibin Leng
| Color Research & Application Verified
IL-37 is emerging as an anti-inflammatory cytokine, particularly in innate inflammation. However, the role of IL-37 in Th2-mediated allergic lung inflammation remains uncertain. We sought to determine the role and the underlying mechanisms of IL-37 in the development of house dust mites (HDM)-induced murine asthma model. We examined the effect of IL-37 administration during the sensitization or challenge phase on Th2-mediated allergic asthma induced by inhaled HDM.
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BLT1 Mediates Bleomycin-Induced Lung Fibrosis Independently of Neutrophils and CD4+ T Cells

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By Jiaoyan Lv, People's Republic, Yingluo Xiong, Wenjing Li
| The Journal of Immunology Verified
BLT1 Mediates Bleomycin-Induced Lung Fibrosis Independently of Neutrophils and CD4+ T Cells Jiaoyan Lv, Yingluo Xiong, Wenjing Li, Wei Yang, Lina Zhao, Rui He The Journal of Immunology February 15, 2017, 198 (4) 1673-1684; DOI: 10.4049/jimmunol.1600465
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