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Antimicrobial Chemotherapy Brief Report INTRODUCTION Cefiderocol is a novel siderophore cephalosporin used to treat severe sepsis infection caused by multidrug-resistant gram-negative bacteria. The chemical structure of cefiderocol comprises a core β-lactam ring, a pyrrolidinium group that enhances stability against β-lactamases, and a carboxypropanoxyimino group on the C-7 side chain, which facilitates transport across the bacterial outer membrane (1).
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