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Young‐onset type 2 diabetes-Epidemiology, pathophysiology, and management
INTRODUCTION Research on the pathophysiology, complications, and management of young-onset type 2 diabetes has accelerated in the past decade due to increasing prevalence and incidence observed in many parts of the world, and a growing recognition of the more adverse prognosis compared with later-onset type 2 diabetes. The COVID-19 pandemic has highlighted the vulnerability of young individuals with type 2 diabetes, who were less likely to survive than age-matched peers without diabetes.
Comparison of beta-cell function between Hong Kong Chinese with young-onset type 2 diabetes and late-onset type 2 diabetes
Lascar N. Brown J. Pattison H. Barnett A.H. Bailey C.J. Bellary S. Type 2 diabetes in adolescents and young adults. Lancet Diabetes Endocrinol. 2018; 6: 69-80https://doi.org/10.1016/S2213-8587(17)30186-9 Magliano D.J. Sacre J.W. Harding J.L. Gregg E.W. Zimmet P.Z. Shaw J.E. Young-onset type 2 diabetes mellitus - implications for morbidity and mortality. Nature reviews Endocrinology. 2020; 16: 321-331https://doi.org/10.1038/s41574-020-0334-z Luk A.O.Y. Ke C. Lau E.S.H. et al.
Low/intermediate speed impact‐induced ignition and damage of a novel high‐energy solid propellant
Abstract The damage and ignition response of a novel propellant is investigated using a modified split Hopkinson pressure bar (SHPB). The mechanical response of the propellant exhibits strong strain rate dependency following a power law. The whole process from mechanical damage to onset of ignition, deflagration and potential deflagration to detonation transition (DDT) under different strain rates (1000–5000 s−1) is captured via high-speed photography and digital image correlation (DIC).
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