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Yingning Ji on Muck Rack

Yingning Ji

As seen in: Journal of Endocrinology
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Articles

Loss of transketolase promotes the anti-diabetic role of brown adipose tissues

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By Yingning Ji, Wei Liu, Yemin Zhu, Yakui Li
| Journal of Endocrinology Verified
Oxidative stress contributes to TKT-dependent TXNIP regulation. (A) qPCR analysis of TKT and TXNIP from brown adipocyte cells (BAC) transfected with negative control shRNAs (shNC) or shRNAs for TKT (shTKT). (B) Western blot analysis of TKT and TXNIP protein levels in BAC transfected with shNC or shRNAs for TKT (shTKT1 and shTKT2). β-actin is the loading control. (C) Levels of NADPH in BAC transfected with shNC or shTKT. (D) Levels of NADPH in BAT from WT and TKTAKO mice (n = 3).
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