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An In Situ Self‐Responsive Nano‐Prodrug to Enable Tumor Chemo‐Metalloimmunotherapy
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm73195-sup-0001-SuppMat.docx18.8 MB Supporting Information References 1, , , , , , , , , , , , , , Genes Diseases 2023, 10, 1367. 2, , , , , , , , , J. Clin. Oncol. 2020, 38, 19299. 3, , , , Maturitas 2017, 105, 23. 4, , , , Int. J. Cardiol.
MnCO3-Au nanoparticles to enable catalytic tumor inhibition with immune activation
MnCO3–Au nanoparticles to enable catalytic tumor inhibition with immune activation† Catalytic nanomedicine, activated by endogenous stimuli to enable specific tumor inhibition, has attracted extensive interest in recent years. However, its therapeutic outcomes are often restrained by the weakly acidic microenvironment and limited H2O2 endogenous content. Here, in this study, gold nanoparticles (AuNPs) with glucose oxidase-like activity are incorporated with biodegradable MnCO3 nanoparticles.
MnCO3-Au nanoparticles to enable catalytic tumor inhibition with immune activation
MnCO3-Au nanoparticles to enable catalytic tumor inhibition with immune activation Catalytic nanomedicine, activated by endogenous stimuli to enable specific tumor inhibition, has attracted extensive interest in recent years. However, its therapeutic outcomes are often restrained by the weakly acidic microenvironment and limited H2O2 endogenous content. Here in this study, gold nanoparticles (AuNPs) with glucose oxidase-like activity are incorporated with biodegradable MnCO3 nanoparticles.
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