Yingping Zhuang

Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Raw data can be made available upon reasonable request. The mass spectrometry proteomic data have been deposited to the ProteomeXchange Consortium with the dataset identifier PXD070628. Supporting Information Filename Description bit70253-sup-0001-Supplementary_materials.docx27.5 MB Figure S1: CER under steady-state chemostat conditions at D = 0.35 h−1.

Conflicts of Interest There are no conflicts of interest to declare. Supporting Information Filename Description biot70024-sup-0001-SuppMat.pdf3.7 MB Supporting information References 1, , and , “Crabtree Effect in Yeast: A Phosphate Tug-of-War Between Fermentation and Respiration,” Trends in Biochemical Sciences 50 (2025): 89–91. 2, “Observations on the Carbohydrate Metabolism of Tumours,” Biochemical Journal 23 (1929): 536–545.

Open AccessArticle by Lan Li , Zejian Wang *, Ali Mohsin and Yingping Zhuang * State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology, Shanghai 200237, China * Authors to whom correspondence should be addressed.