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Yingqian Chai

As seen in: Wiley Online Library
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Articles

Efferocytosis-Mimicking Nanovesicle-Cross-Linked Hydrogel for Dual Immunomodulation and Angiogenesis to Prolong Allogeneic Skin Graft Survival

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By Shanshan Yuan, Yingqian Chai, Zheng Li, Lihua Jiang
| dx.doi.org
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Engineering Efferocytosis‐Mimicking Nanovesicles to Regulate Joint Anti‐Inflammation and Peripheral Immunosuppression for Rheumatoid Arthritis Therapy

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By Shanshan Yuan, Jianghua Xu, Youchao Wang, Yingqian Chai
| Wiley Online Library Verified
1 Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint and systemic inflammation.[1-3] The dysfunction of regulatory T cells (Tregs) plays a crucial role in the breakdown of self-tolerance,[4, 5] leading to a proliferative autoimmune disorder within the peripheral blood and the infiltration of inflammatory immune cells (including proinflammatory M1 macrophages[6, 7] and pathogenic CD4+ T cells[8, 9]) into the synovial membrane.
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