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Yingrong He

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Articles

Progresses in Questing for the Truth of Opioid‐Related Constipation in Cancer Patients

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By Mengxue Liu, Yedong Sheng, Yingrong He, Shixiang Wu
| Wiley Online Library Verified
1 Introduction Both the incidence and mortality rates of malignant tumours, a leading cause of death, are on the rise in China [1]. Pain appears in 69% of cancer patients [2], and the use of opioids causes OIC in up to 60%–90% of these patients [3]. The pathogenesis of OIC is complex, making it challenging to develop effective therapeutic interventions. Therefore, this review aims to delve into the pathogenesis of OIC, identify potential therapeutic targets and propose research directions.
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