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NAD+ Enhanced on Hearing Recovery in Sudden Sensorineural Hearing Loss: Randomized Controlled Trial
1 Introduction Sudden sensorineural hearing loss (SSNHL) occurs rapidly within 72 h, with a hearing loss of at least 30 dB over three frequencies. It often includes tinnitus (90% of cases), aural fullness (50% of cases), dizziness, or other ear-related symptoms. SSNHL affects 5–27 per 100,000 individuals annually in the United States, 60.9 per 100,000 in Japan, and 0.59% in China [1-3]. Its causes are mostly unknown but may involve vascular issues, inner ear problems, or viral infections [4].
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