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Yingtong Hou

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Articles

Integrated multi-omics and single-cell analyses identify metabolic heterogeneity and therapeutic vulnerabilities in medullary thyroid cancer

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By Chuqiao Liu, Cenkai Shen, Yingtong Hou, Yuxin Du, Yihao Liu, Danni Liu, Yan Zhang, Xiaoqi Mao, Yujian Song, Zimeng Li, Qinghai Ji, Xiao Shi, Yu Wang, Wenjun Wei
| Nature Verified
Abstract Medullary thyroid cancer (MTC) is a heterogeneous and aggressive malignancy with limited therapeutic options. Metabolic reprogramming, a hallmark of cancer, may offer a promising avenue for understanding and managing MTC. RNA sequencing data of 101 MTC samples were obtained from a published dataset PRJCA008783, and untargeted metabolomic profiling was performed on 51 paired samples.
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