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Yingwei Ou

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Articles

Advances in the Clinical Application of Histamine and Diamine Oxidase (DAO) Activity: A Review

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By Zhaowang Tan, Yingwei Ou, Wenwei Cai, Yueliang Zheng
| MDPI
1. Introduction Diamine oxidase (DAO) is a secretory protein located in the cytoplasm of human and mammalian upper intestinal mucosa chromaffin cells and is responsible for catabolizing histamine (mainly extracellular) to stop allergic reactions [1]. DAO level is extremely low in peripheral blood; this enzyme is mainly distributed in the intestine and abundant in the kidney, placenta, and other organs [2].
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