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Yingwei Zhu on Muck Rack

Yingwei Zhu

As seen in: Nature, The Oncologist, Taylor & Francis Online, ACS Publications, Respiratory Research, Royal Society of Chemistry, Respiratory Medicine
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Articles

α-ketoglutarate accumulation orchestrates immunosuppressive metabolic remodeling to drive cetuximab resistance in metastatic colorectal cancer

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By Yingwei Zhu, Ling Chang, Jian Lu, Hong Tang, Zhenxin Zhu, Zhiru Chen, Xiongjun Wang, Jing Xiao, Kuijie Liu
| Nature Verified
Abstract Cetuximab resistance remains a major obstacle in the treatment of metastatic colorectal cancer (mCRC), highlighting the urgent need to identify synthetic lethal partners of EGFR. In this study, we observed glutamate dehydrogenase 1 (GDH1) accumulation in cetuximab-treated CRC samples. GDH1 depletion sensitized CRC cells to cetuximab and suppressed remodeling of the tumor immune microenvironment (TIME), as revealed by single-cell RNA sequencing.
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A comprehensive panel of testing for amyloidosis

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By Hong Tang, Feifei Zhao, Yingwei Zhu, Rongrong Xu
| Taylor & Francis Online
ABSTRACT Amyloidosis encompasses a spectrum of rare disorders characterized by extracellular amyloid deposition. Achieving an accurate early diagnosis of systemic amyloidosis necessitates biopsy-specific pathological evaluation. Formalin-fixed, paraffin-embedded liver biopsy specimens were examined using Congo red staining, electron microscopy, immunohistochemistry (IHC), immunofluorescence, and Congo red-assisted laser microdissection with mass spectrometry (LMD/MS).
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Analysis of Clinical Characteristics in 1940 Patients with Acute Pulmonary Embolism

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By Bo Chen, Wei Wang, Wenqian Zang, Jinjin Hu, Hengyun Li, Cong Wang, Yingwei Zhu, Yimin Mao, Pengfei Gao
| Respiratory Medicine Verified
Keywords Acute pulmonary embolism Clinical characteristic Risk stratification Get full text access Log in, subscribe or purchase for full access. References 1. Goldhaber, S.Z. ∙ Bounameaux, H. Pulmonary embolism and deep vein thrombosis Lancet. 2012; 379:1835-1846 2. Di Nisio, M. ∙ van Es, N. ∙ Büller, H.R. Deep vein thrombosis and pulmonary embolism Lancet. 2016; 388:3060-3073 3. Wendelboe, A.M. ∙ Raskob, G.E. Global Burden of Thrombosis: Epidemiologic Aspects Circ Res. 2016; 118:1340-1347 4.
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