Yingxia Zheng
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Single cell transcriptomics analyses reveal functional heterogeneity and anti-tumor role of mast cells in esophageal squamous cell carcinoma
Abstract Introduction: Mast cells (MCs) play important roles in allergic reactions and tissue homeostasis; however, their functions in esophageal squamous cell carcinoma (ESCC) remain controversial. Understanding the heterogeneity and functional states of MCs in ESCC is essential for elucidating their roles in tumor progression and immune regulation.
Comparative profiling of amino acids in plasma and serum across children and adults using LC–MS/MS and its implications for precision nutrition
Abstract Objective: Circulating amino acids (AAs) are important biomarkers of nutritional status, metabolic homeostasis, and disease related physiological changes. However, the influence of specimen type and age on AA measurements remains incompletely understood.
PRMT5 Deficiency Enforces the Transcriptional and Epigenetic Programs of Klrg1+CD8+ Terminal Effector T Cells and Promotes Cancer Development
Introduction Similar to phosphorylation and acetylation protein post-translational modifications, protein arginine methylation plays a critical role in the fields of epigenetics and signal transduction (1, 2).
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