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Zanubrutinib-rituximab followed by shortened chemoimmunotherapy as frontline treatment for mantle cell lymphoma (CHESS): a phase II trial
Abstract A combination of Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib and rituximab has shown promising efficacy in mantle cell lymphoma (MCL). This phase II trial evaluated the second-generation BTK inhibitor zanubrutinib plus rituximab as induction, followed by shortened chemoimmunotherapy as frontline treatment for MCL (NCT04624958). Eligible patients had histologically confirmed stage II–IV disease requiring immediate therapy and no prior MCL-related systemic treatment.
Artificial Intelligence in CT for Predicting Cervical Lymph Node Metastasis in Papillary Thyroid Cancer Patients: A Meta-analysis
Abbreviations LNM (lymph node metastasis) PTC (papillary thyroid cancer) DECT (dual-energy CT) TP (true positive) TN (true negative) FP (false positive) FN (false negative) ROC (receiver operating characteristic) CI (confidence intervals) SROC (summary receiver operating characteristic) AI (artificial intelligence) AUC (area under the curve) Key Words Artificial intelligence Computed tomography Papillary thyroid cancer Lymph node metastasis Meta-analysis Get full text access Log in, subscribe...
Study on Surfactant-Polymer Flooding after Polymer Flooding in High-Permeability Heterogeneous Offshore Oilfields: A Case Study of Bohai S Oilfield
1. Introduction In recent years, with the declining discovery of new petroleum reserves, enhancing oil recovery (EOR) technologies have become pivotal for meeting future energy demands [1]. Well-known chemical EOR techniques include polymer flooding, surfactant flooding, and alkaline flooding [2,3]. Among these, polymer flooding has been employed in the petroleum industry for over 40 years [4], demonstrating the potential to increase the recovery efficiency of geological reserves by 5–30% [5].
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