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Extreme Kinetic Stability and RNase Resistance of Human Telomerase RNA G‐Quadruplexes Overcome by DHX36 Helicase
1 Introduction Guanine-rich RNAs can fold into four-stranded secondary structures known as G-quadruplexes(G4s). These structures are prevalent across various RNA species, including mRNA, microRNA, and long non-coding RNA (lncRNA), and are implicated in diverse biological processes [1-3], such as translation regulation [4, 5], mRNA splicing [6], enzymatic activity modulation [7], and telomere maintenance [8, 9].
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