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Yingxiao Gao

As seen in: Nature, Wiley Online Library
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Articles

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

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By Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu
| Wiley Online Library Verified
1 Introduction Lysine methylation, as a common and important post-translational modification (PTM), plays significant roles in gene transcription regulation, cell cycle control, DNA damage repair, and other cellular processes.[1-6] For instance, histone H3 lysine 4 trimethylation (H3K4me3) is involved in gene transcriptional activation, while H3K27me3 is related to gene transcriptional repression.[1] Abnormalities in lysine methylation are also associated with the occurrence and development...
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Single-electron transfer between sulfonium and tryptophan enables site-selective photo crosslinking of methyllysine reader proteins - Nature Chemistry

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By Yingxiao Gao, Lihua Zhang
| Nature Verified
Abstract The identification of readers, an important class of proteins that recognize modified residues at specific sites, is essential to uncover the biological roles of post-translational modifications. Photoreactive crosslinkers are powerful tools for investigating readers.
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A General Method to Edit Histone H3 Modifications on Chromatin Via Sortase‐Mediated Metathesis

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By Qingyun Yang, Yingxiao Gao, Xia Liu, Yihang Xiao
| Wiley Online Library Verified
As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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