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Yingxin Chen on Muck Rack

Yingxin Chen

As seen in: Color Research & Application, Nature, Wiley Online Library, BMJ Open, Frontiers, Frontiers in Medicine, MDPI, ACS Publications, Science Magazine, Royal Society of Chemistry and
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Articles

Effectiveness of 0.05% cyclosporine A eye drops for dry eye disease in patients with thyroid-associated ophthalmopathy: a prospective, parallel-group cohort study

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By Yu ZHANG, Juan Bao, Cuiyu Wang, Ruiyao Gao, Kai Zhang, Yingxin Chen
| Frontiers in Medicine
Abstract Background: Thyroid-associated ophthalmopathy (TAO) is frequently accompanied by dry eye disease (DED), which can lead to ocular surface damage and decreased visual quality. This study aimed to evaluate the effectiveness of 0.05% cyclosporine A (CsA) eye drops in the treatment of TAO-related DED. Methods: This prospective, parallel-group cohort study included 86 participants diagnosed with TAO-related DED.
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Dynamic microenvironments for bone organoids: spatiotemporal regulation of angiogenic-osteogenic coupling through advanced hydrogel design

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By Sen Liu, Lang Tian, Yayue Zheng, Yingxin Chen, Yangjun Liu, Xiujie Wen
| Frontiers
Abstract Bone organoids are promising platforms for studying skeletal development, disease and regeneration, but their broader application is limited by inadequate vascularization and the difficulty of recapitulating the evolving native bone microenvironment. In vivo, angiogenesis and osteogenesis are tightly coupled processes that overlap spatially and temporally, with their relative dominance shifting during tissue development and repair.
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Electroactive microneedle augmented stem cell therapy in myocardial infarction

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By Valdemar Priebe, Peter Sheridan Dodds, Mohammad A Saad, Wentao Zhang, Yiqi Shen, Shuangxu Jia, Yingxin Chen, Ruisi Cai, Yunlong Jiao, Quanquan Han, Jiahuan You, Shiqi Wang, Xingyi Wan, Jicheng Yu, Zhen Gu, Zhuxiao Gu, Yuqi Zhang
| Science Magazine Verified
Abstract Ischemic heart disease and related sequelae pose tremendous burdens on worldwide medical care. The excessive activation of cardiomyocytes and cardiac fibroblasts further exacerbates the prognosis after necrosis. Decades of stem cell therapy in preclinical studies suggested promising results in cardiomyocyte regeneration and tissue remodeling. However, few formulations achieved clinical translation due to the limited stem cell engraftment and insufficient arousal of resident cardiomyocytes.
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