Yingxin Fu

Abstract Post-transcriptional regulation via the mRNA poly(A) tail is fundamental to gene expression, yet a comprehensive dataset across an entire organism is still lacking. Here, we generated a pan-organ atlas of poly(A) tail lengths across 18 murine organs using full-length nanopore sequencing that totaled 422 million reads. This dataset enables robust, single-molecule poly(A) profiling for an average of 7421 genes per sample (≥20 reads).

1. Introduction Electroencephalogram (EEG) devices are widely used to record brain signals in brain–computer interface (BCI) systems because of their non-invasiveness, high temporal resolution, and relatively low cost [1]. Motor imaginary (MI) is defined as the mental stimulation of particular limb movement (such as hands, feet, and tongue), and the execution of MI can evoke similar somatotopically organized activation patterns [2,3].