Yingxin Wang
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Construction and validation of an interpretable machine learning model for predicting diabetes risk in COPD patients
Abstract To construct and validate a machine learning (ML) model for predicting diabetes risk in COPD patients, enabling early and personalized intervention. Using data from the MIMIC-IV database, 49 variables were screened by LASSO and logistic regression. Six ML algorithms were constructed and internally validated on a 70%/30% split dataset. Model performance was assessed using multiple metrics, followed by external validation. Interpretability was achieved through SHAP analysis.
E3 Ubiquitin Ligase Nedd4-2 Exacerbates Seizure-Induced Mitochondrial Defects in an Alzheimer's Disease Mouse Model
AD Alzheimer's disease APP amyloid precursor protein Aβ amyloid-β cKO conditional knockout COX IV cytochrome C oxidase subunit 4 DIV days-in vitro DMSO Dimethyl sulfoxide GAPDH glyceraldehyde-3-phosphate dehydrogenase HEK human embryonic kidney MAP 2 microtubule-associated protein 2 MFN2 mitofusin 2 Nedd4-2 neural precursor cell-expressed developmentally downregulated protein 4-like NRF1 nuclear respiratory factor 1 PS1 presenilin I ROS reactive oxygen species TOM20 translocase of outer...
Radiotherapy-synergized in situ hydrogel vaccine with engineered Lactococcus lactis FOLactis potentiates anti-tumor immunity in pancreatic cancer
Abstract Background: Immunotherapy has emerged as a promising strategy for pancreatic cancer. Radiotherapy not only mediates direct tumor cell killing but also provides a source of tumor antigens for dendritic cells (DCs) uptake and presentation via the induction of immunogenic cell death (ICD).
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