Yingxuan Huang

Abstract Objectives: Gastroesophageal reflux disease (GERD) is a common chronic digestive disorder, and diet is an important modifiable risk factor. The Dietary Index for Gut Microbiota (DI-GM) reflects dietary patterns considered favorable to the gut microbiota; however, the gut microbiome itself was not measured, and evidence on whether DI-GM is associated with GERD risk is limited.

Data Availability Statement All data generated or analyzed during this study are included in this article. Further enquiries can be directed to the corresponding author. Supporting Information Filename Description jbt70712-sup-0001-Supplementary_Figure_1.tif956.5 KB Supporting Figure 1: Transfection efficiency validation. A-B. RT-qPCR confirmation of (A) KCNJ2-AS1 and (B) miR-212-3p knockdown. Data are presented as the mean ± SD of four independent experiments (A-B). (p < 0.001***).

Abstract This study developed an immune-related long non-coding RNAs (lncRNAs)-based prognostic signature by integrating multi-omics data and machine learning algorithms to predict survival and therapeutic responses in breast cancer patients. Utilizing transcriptomic and gene expression data from TCGA and GEO databases, 72 immune-related lncRNAs were identified through weighted gene co-expression network analysis (WGCNA) and ImmuLncRNA algorithms.