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Yingxue Che

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Machine and Deep Learning Reveal Sequence Determinants Encoding Bivalent Histone Modifications

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By Xinyu Zhao, Jie Wu, Chunshen Long, Yongqiang Xing, Hanshuang Li, Yongchun Zuo, Yingxue Che
| Nature Verified
Abstract Bivalent histone modifications, marked by the coexistence of activating and repressive histone marks, define a distinctive chromatin state with key roles in developmental gene regulation. However, the specific sequence features that distinguish bivalent chromatin regions remain unclear.
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