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Yingya Li on Muck Rack

Yingya Li

As seen in: Frontiers
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Articles

CCN1-induced senescence and dysfunction of umbilical cord blood endothelial colony-forming cells in the pathogenesis of preeclampsia

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By Yuyang Ma, Fenglian Yang, Yu Wang, Yanping Jia, Jie Wang, Kunming Li, Liyan Duan, Yingya Li
| Frontiers
Abstract Introduction: Maternal vascular dysfunction and impaired placental angiogenesis are key features of preeclampsia (PE). Umbilical cord blood-derived endothelial colony-forming cells (CB-ECFCs) contribute to fetal endothelial repair and vascular network formation, but their phenotype in PE remains incompletely understood. Methods: We investigated whether the matricellular protein CCN1 is associated with CB-ECFC senescence and dysfunction.
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