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Exogenous insulin autoimmune syndrome: a case report and literature review
1 Introduction Exogenous Insulin Autoimmune Syndrome (EIAS) is a rare disorder triggered by the administration of exogenous insulin, leading to an autoimmune response. It is characterized by the production of high titers of insulin autoantibodies (IAA), which reversibly bind to insulin. The dissociation of insulin from these immune complexes can cause unpredictable and severe glycemic variability, including recurrent hypoglycemic episodes and intermittent hyperglycemia.
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