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Yingyi Ning

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Articles

A Stepwise‐Enhanced Schottky Heterojunction Enables Ultra‐Low‐Dose Radiodynamic Therapy via Matrix Remodeling and Electron-Hole Separation

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By Chaoyi Lyu, Yanbin Chen, Yingyi Ning
| Wiley Online Library Verified
1 Introduction Radiation therapy (RT) directly disrupts DNA structures or generates cytotoxic reactive oxygen species (ROS) through high-energy ionizing radiation [1-3], thereby suppressing tumor cell proliferation. It has been a crucial clinical approach in cancer treatment in the last century [4, 5]. However, high-dose RT inevitably damages healthy tissues because of the slight difference in radiosensitivity between normal and tumor cells [4, 6], severely limiting its clinical efficacy.
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