Yingying Song
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Transcription factor Tono mediates histone H3K4 trimethylation to regulate endoreplication through transcriptional reprogramming
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Endoreplication is a cell cycle variant that involves multiple rounds of DNA replication without cell division, resulting in enlarged cells and organs.
Generative pretraining for drug molecule design with bidirectional structure-property optimization
Abstract Designing drug-like molecules that satisfy both properties requirements and structural constraints remains challenging. Current generative approaches typically reduce properties to numerical constraints and treat molecular structures as deterministic functions of properties, failing to capture complex, nonlinear structure-property relationships and limiting generative diversity and controllability.
Dual phosphorylation of StCAMTA3 mediated by distinct calcium sensors orchestrates potato immunity
Data availability All data needed to evaluate the conclusions in the paper are present in the paper and/or the Supporting Information (Figs ; Tables ).
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