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Yingzhe Xiong on Muck Rack

Yingzhe Xiong

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Articles

Breviscapine attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis via activation of NRF2/SLC7A11/GPX4 pathway

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By Yingzhe Xiong, Jiawei Wu, Qiangqiang Tian, CHEN CHEN, An’an Tan
| Nature Verified
Abstract To explore the protective effect of Breviscapine against myocardial ischemia-reperfusion (I/R) injury and its mechanism. The in vivo and in vitro models of myocardial I/R injury were first established and treated with different concentrations of Bre. The myocardial infarct size was measured, while histopathological changes of myocardial tissue were evaluated by hematoxylin-eosin (HE) staining, and cardiac function-related parameters were assessed via echocardiography.
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