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Kaurenoic Acid Suppresses Osteosarcoma Progression by Reprogramming Tumor‐Associated Macrophages to M1 Phenotype
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description ddr70183-sup-0001-Supplementary_files.docx24.6 MB Figure S1: Differentiation of THP-1 cells into M1 and M2 macrophage phenotype. Figure S2: KA exerted anti-OS effects in vitro by activating MAPK and NF-κB signaling pathways in M2 macrophages. Figure S3: Safety evaluation of KA in OS-bearing mice. ddr70183-sup-0002-Table.docx17.8 KB Table S1: RT-PCR primers used in this study.
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