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Yingzhi Wang on Muck Rack

Yingzhi Wang

As seen in: Nature, Wiley Online Library, MDPI, Royal Society of Chemistry, BioRxiv, International Journal of Infectious Disease
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Articles

A unique mechanism of snRNP core assembly - Nature Communications

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By Yingzhi Wang, Shijie Zhou
| Nature Verified
Abstract The assembly of most spliceosomal snRNP cores involves seven Sm proteins (D1/D2/F/E/G/D3/B) forming a ring around snRNA, typically requiring essential assembly chaperones like the SMN complex, associated with spinal muscular atrophy (SMA). Strikingly, in budding yeast, snRNP core assembly only involves Brr1, a nonessential homolog of Gemin2.
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De Novo Negatively Charged Binders Targeting MMLVRT Nucleic Acid Binding Sites Overcome Stability-Activity Trade-offs

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By Yibo Zhu, Hongwei Liu, Fang Qu, Yingzhi Wang
| BioRxiv
Abstract The limited thermostability and storage-induced inactivation of Moloney murine leukemia virus reverse transcriptase (MMLV RT) have constrained its applications. In this study, a high-stability mutant, MMLV RT-SV, was generated through a multi-site mutagenesis strategy targeting the nucleic acid-binding pocket.
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Inverse Coupled Simulated Annealing for Enhanced OSPF Convergence in IoT Networks

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By Chengsheng Pan, Huangjie Lu, Yingzhi Wang, Huaifeng Shi
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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