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Yingzhou Hu on Muck Rack

Yingzhou Hu

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Articles

Nigral DJ-1 gene knockout in tree shrews can induce phosphorylated α-synuclein aggregation and all key phenotypes of Parkinson’s disease

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By Leyi Mei, Jingmei Cha, Xinze Li, Jitong Yang, Xiaoguang Lei, Yuhua Ma, Wenchao Wang, Xiaofeng Ren, Jing Cynthia Wu, Yuhua Zhang, Rong Tang, Longbao Lv, Christoph W. Turck, Bingyu Mao, Xintian Hu, Yingzhou Hu
| Nature Verified
Abstract DJ-1 is a genetic factor associated with Parkinson’s disease (PD), and altered DJ-1 function has been implicated in PD pathogenesis. However, DJ-1 knockout mice fail to reproduce robust PD-like phenotypes or neuropathology, leaving the contribution of DJ-1 deficiency to PD-related disease processes unresolved.
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