Yini Dang

1 Introduction Alzheimer's disease (AD) is the leading cause of dementia among older individuals [1], characterized by senile plaques and neurofibrillary tangles resulting from abnormal Aβ aggregation and tau protein phosphorylation [2]. Aβ peptides are generated through the cleavage of amyloid β precursor protein (APP) by β- and γ-secretase [3].

Xintong Zhang1*, Xiangyu Wang2, Shuwei Wang3, Yingjie Zhang1, Zeyu Wang4, Qingyan Yang1, Song Wang5, Risheng Cao1, Binbin Yu1, Yu Zheng1 and Yini Dang1 1First Affiliated Hospital, Nanjing Medical University, China 2The Affiliated Lianyungang Oriental Hospital of Kangda College of Nanjing Medical University, China 3Taizhou hospital of Zhejiang province affiliated to Wenzhou medical university, China 4Shanghai Ruijin Rehabilitation Hospital,, China 5Wuxi Yihe Rehabilitation Hospital, China...