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Yini Huang on Muck Rack

Yini Huang

As seen in: Nature, Frontiers
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Articles

Circadian–immune crosstalk in insomnia disorder: mechanisms and therapeutic implications

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By Yini Huang, Xiuying Wang, Yan Liu, Xiangjiao Chen
| Frontiers
Abstract Insomnia disorder (ID) is a common sleep–wake disorder characterized by persistent difficulty initiating or maintaining sleep, early-morning awakening, or non-restorative sleep, accompanied by daytime functional impairment. ID has traditionally been explained by the hyperarousal model, which emphasizes cognitive, emotional, cortical, neuroendocrine, and autonomic overactivation.
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Comparative effectiveness of traditional Chinese medicine treatment strategies for insomnia: a systematic review and network meta-analysis

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By Yan Liu, Xiuying Wang, Yaqin Zhang, Yanfang Li, Yini Huang
| Frontiers
Abstract Objective: Insomnia causes daytime impairment and reduced quality of life. We evaluated the comparative efficacy and safety of Traditional Chinese Medicine (TCM) treatment strategies for insomnia. Methods: Nine databases (PubMed, Embase, Web of Science, Cochrane CENTRAL, ClinicalTrials.gov, CNKI, Wanfang, VIP, SinoMed) were searched through January 2026 for randomized controlled trials (RCTs).
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Tuspetinib enhances the activity of polymyxin B by inhibiting the GlcNAc6P deacetylase

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By Yu Ouyang, Jinyong Zhang, Yini Huang, Dengpan Liang, Xinyue Wu, Xiaopeng Yuan, Xitao Li, Quanming Zou, Wei Huang, Chao Lu, Ruiqin Cui
| Nature Verified
Abstract The past decade has witnessed the recognition of antibiotic resistance as an emerging threat to public health. Polymyxin B (PMB) is a last-resort antibiotic against multidrug-resistant (MDR) Gram-negative bacteria, but it has nephrotoxicity. A cocktail with molecules to sensitize microbes to PMB is an effective approach to rescue and expand its clinical application range.
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