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Yining Xiao on Muck Rack

Yining Xiao

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ELK1 suppressed the progression of vascular dementia via modulating mTOR/CREB/YAP/TFEB signaling induced ferroptosis in hippocampal cells - Scientific Reports

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By Jing Xu, Miaomiao Liu, Qianqian Qi, Jin An, Tianyuan Guan, Zhenjie Teng, Weihong Chen, Rui Li, YanHong Dong, Peiyuan Lu, Yining Xiao, Yanzhong Chang
| Nature Verified
Abstract To investigate the effects of ELK1 on hippocampal cells and its related mechanisms in the progression of vascular dementia (VD). Twenty-seven SD rats were divided into three groups: sham group (n = 9), Model group (n = 9), and Model+ELK1-OE group (n = 9). The VD animal model was established in the Model group by bilateral common carotid artery occlusion (BCCAO). The Morris water maze test was performed to observe the learning and memory abilities of the rats in the three groups.
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