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Systemic extracellular acidification is a hallmark of aging
Abstract Understanding the critical pathophysiological processes that promote age-related disease is needed to uncover effective targets for preventive medicine. Here, we investigate how extracellular pH changes with age and its impact on longevity, using fly and mouse models. We find that extracellular acidification occurs in flies during aging and correlates to mortality rate. With age, flies also become more susceptible to die from acidotic stress, which can be prevented by alkalotic treatment.
High piezoelectricity induced by lattice distortion and domain realignment in Li2CO3-added lead-based ceramics
High piezoelectricity induced by lattice distortion and domain realignment in Li2CO3-added lead-based ceramics The 0.2Pb(Ni1/3Nb2/3)O3-0.1Pb(Zn1/3Nb2/3)O3-0.7Pb(Zr0.46Ti0.54)O3+xwt% Li2CO3 ceramics were synthesized by the solid-state reaction method. After doping Li+ ions into the ceramics, the [BO6] oxygen octahedra stretch along the direction of the spontaneous polarization (Ps), which increases the Ps and improves the internal contribution to the piezoelectric properties.
Mathematics | Free Full-Text | Stability Analysis and Hopf Bifurcation of a Delayed Diffusive Predator-Prey Model with a Strong Allee Effect on the Prey and the Effect of Fear on the Predator
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1, 1 and 2,* 1 School of Mechanical and Electrical Engineering, Northeast Forestry University, Harbin 150040, China 2 Department of Mathematics, Northeast Forestry University, Harbin 150040, China * Author to whom correspondence should be addressed.
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