Yinjun Huang

1 Introduction Spinal cord ischemia–reperfusion injury (SCI) is a severe neurological condition that arises from the transient interruption of spinal cord blood flow, followed by the restoration of circulation [1, 2]. The reperfusion phase initiates a cascade of complex cellular and molecular events, including excessive oxidative stress, the generation of reactive oxygen species, activation of local and systemic inflammatory responses, and widespread neuronal apoptosis or necrosis [3, 4].