Yinkai Yang

Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The single-cell and bulk RNA sequencing data generated in this study have been deposited to NCBI with the accession number PRJNA1206684 (http://www.ncbi.nlm.nih.gov/bioproject/1206684). The raw transcriptome data for the OpAVT1-KO1 hairy root line is now available under NCBI accession number PRJNA1329249 (http://www.ncbi.nlm.nih.gov/bioproject/1329249). The genome of O.

1 Introduction Salvia miltiorrhiza (Danshen) is a valuable traditional Chinese medicinal plant widely used for treating cardiovascular and cerebrovascular diseases (Wang et al. 2017; Wei et al. 2023). The roots of S. miltiorrhiza accumulate tanshinones, which are diverse abietane diterpenoids including cryptotanshinone (CT), tanshinone IIA (TIIA), dihydrotanshinone (DHT) and tanshinone I (TI) (Jiang et al. 2019). These representative compounds mainly compose the bioactive ingredients of S.

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