Abstract Objective: This study evaluated the anti-obesity effects of Ginseng-Douchi (SC), a novel functional food fermented from ginseng and soybean (both medicinal and edible resources) using Bacillus subtilis, and explored its gut microbiota regulatory mechanisms in high-fat diet (HFD)-induced obese mice. Methods: C57BL/6 mice were fed an HFD to induce obesity and then randomly assigned to normal-control, HFD model, orlistat positive-control, and SC low-, medium-, and high-dose groups.
