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Yinping Shi

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Articles

Progress of triazole antifungal agent posaconazole in individualized therapy

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By Yishuo Shu, Shandong Medicine, Yinping Shi, Yilei Yang
| Wiley Online Library Verified
ICU patients Australia 93 concentrations from 8 patients aged 40–51 years Age, Gender, HT, WT, BMI, ALB, SCr, CCr, CRRT, ALT, AST, ALK, TBIL, GGT Albumin and BMI C free = C total × FF × Alb median Alb $$ {C}_{free}={C}_{total}\times FF\times \frac{Alb_{median}}{Alb} $$ C bound = B max × C free K D + C free $$ {C}_{bound}=\frac{B_{max}\times {C}_{free}}{K_D+{C}_{free}} $$ B max = Alb × N × M posa M Alb × 1000 $$ {B}_{max}= Alb\times N\times \frac{M_{posa}}{M_{Alb}}\times 1000 $$ V = V × BMI /...
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