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ABCF2 is a prognostic and immunological pan-cancer biomarker with growth-promoting function in breast cancer: a multi-omics study
Abstract Background: Unlike canonical members of the ABC transporter superfamily, ATP-binding cassette sub-family F member 2 (ABCF2) carries no transmembrane domains and participates in translational regulation. Nevertheless, its expression pattern, prognostic importance, genetic and epigenetic control, and immune-related effects have not been systematically evaluated across human malignancies, and its biological role and druggability in breast cancer remain unclear.
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