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Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology
1 Introduction Ketamine, chemically designated as C13H16ClNO, and also recognized by its systematic name 2-(2-chlorophenyl)-2-(methylamino) cyclohexanone, is a potent agent within the phencyclidine (PCP) class of pharmaceuticals. This compound, first crafted by the distinguished Professor Calvin Stevens in the year 1962, was subsequently sanctioned for use as an anesthetic in clinical settings in 1970.
Frontiers | Acupuncture improves blood–brain barrier integrity through multi-targeted mechanisms: a preclinical meta-analysis
1Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China 2Guangzhou University of Chinese Medicine, Guangzhou, China 3Department of Acupuncture and Rehabilitation, The Affiliated Traditional Chinese Medicine Hospital of Guangzhou Medical University, Guangzhou, China Objective: The objective of this study is to assess the impact of acupuncture regarding Blood–Brain barrier (BBB) permeability and provide a data foundation for...
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