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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Thiazolidinedione-Conjugated Lupeol Derivatives as Potent Anticancer Agents through a Mitochondria-Mediated Apoptotic Pathway
1. Introduction Cancer is the leading cause of death and has a serious impact on human health worldwide [1,2]. Chemotherapy is a traditional method for treating cancer [3]. However, despite the effectiveness of chemotherapeutic drugs, they can also cause adverse reactions in normal cells and are associated with multidrug resistance (MDR) [4]. Therefore, it is urgent to develop more effective drugs with low toxicity.
Lupeol-3-carbamate Derivatives: Synthesis and Biological Evaluation as Potential Antitumor Agents
1. Introduction Cancer is recognized as one of the most lethal diseases affecting humans, with its annual incidence and mortality rates continuing to be high [1]. At present, a variety of anti-tumor drugs are being developed and applied in clinical practice. Despite clinical use, many anti-tumor drugs are known to have serious side effects, such as those caused by traditional platinum-based anticancer drugs [2,3]. Their broader use is limited due to toxicity and potential drug resistance.
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