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Yinying Lu on Muck Rack

Yinying Lu

As seen in: Frontiers in Immunology, Gut Journal, The Royal Army Medical Corps Journal, Canadian Journal of Infectious Diseases & Medical Microbiology, Dove Medical Press
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Articles

Comparative analysis of immune escape and BCR repertoire remodeling after Omicron BF.7 and JN.1 infections

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By Luxuan Yang, Yulei Sun, Jiayan Li, Yinying Lu, Hongyu Wang, Liangjiu Zhang, Binhuang Sun, Xinyi Yu, Xiaoyu Zhao, Jingwen Ai, Wenhong Zhang, Luanfeng Lin, Yabo Mi, Tianmei Yu
| Frontiers in Immunology
Abstract SARS-CoV-2 Omicron evolution continues to erode antibody-mediated immunity, but whether infection with antigenically distinct lineages simply amplifies pre-existing memory or redirects humoral recognition toward newly evolved antigenic space remains unclear. Here, we analyzed paired early- and convalescent-phase plasma and whole-blood samples from individuals with sequencing-confirmed BF.7 or JN.1 infection.
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A multicenter retrospective real-world study on the efficacy and safet

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By Weihong Ma, Yinyin Li, Yinying Lu, Zhipeng Liang
| Dove Medical Press
Weihong Ma,1,2,* Yinyin Li,1,* Yinying Lu,1,2 Zhipeng Liang,3 Hongli Yu,1,2 Jie Han,1,2 Jiaqi Liu,1,2 Wenjing Wang,1,2 Caiyun Peng,1 Jiamin Cheng1 1Senior Department of Hepatology, The 5th Medical Center of the PLA General Hospital, Beijing, People’s Republic of China; 2Chinese PLA Medical School, Beijing, People’s Republic of China; 3Guizhou Medical University, Guizhou, People’s Republic of China *These authors contributed equally to this work Correspondence: Jiamin Cheng, Email...
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Sodium+/taurocholate cotransporting polypeptide as target therapy for liver fibrosis

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By Ahmad Salhab, Johnny Amer, Yinying Lu, Rifaat Safadi
| Gut Journal Verified
Discussion Our study is the first to describe the presence of NTCP on human liver HSCs obtained from patients with LF. NTCP expression is linearly correlated with fibrosis severity. We also revealed that NTCP mediates BAs uptake in HSCs, triggering their activations. Dysregulation of NTCP through their inhibitions initiated HSC deactivation in an in vitro and in vivo mice model. Targeting NTCP is essential in minimising BAs accumulation in liver and thereby attenuating LF in CCl4-induced mice model.
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